Renal Transport of Urate in Humans.
نویسندگان
چکیده
The theory of the "four-component model" of urate excretion in humans is reevaluated, considering that a decrease in urate excretion induced by drugs like pyrazinamide or by endogenous compounds like lactate and ketone bodies might be a result of stimulation of urate reabsorption and not, as previously considered, of inhibition of urate secretion.
منابع مشابه
NIPS.April.Second Notebook
0886-1714/99 5.00 © 1999 Int. Union Physiol. Sci./Am.Physiol. Soc. 80 The renal urate handling in humans has been explained for many years by a “four-component model.” The purpose of this review is to reevaluate the validity of the theory behind this hypothetical model in the light of the transport mechanisms that were characterized recently in the apical membrane (brush-border membrane; BBM) o...
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عنوان ژورنال:
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
دوره 14 شماره
صفحات -
تاریخ انتشار 1999